Dr. Douglas "Doogie" Howser: | Neil Patrick Harris |
Dr. David Howser: | James B. Sikking |
Katherine Howser: | Belinda Montgomery |
Vinnie Delpino: | Max Casella |
Dr. Benjamin Canfield: | Lawrence Pressman |
Dr. Jack McGuire: | Mitchell Anderson |
Nurse Curly Spaulding: | Kathryn Layng |
Wanda Plenn: | Lisa Dean Ryan |
Janine Stewart: | Lucy Boryer |
Raymond Alexander: | Markus Redmond |
Dr. Ron Welch: | Rif Hutton |
Nurse Michele Faber: | Robyn Lively |